PT-141 - 10 mg

PT-141 10 mg - melanocortin MC4R receptor agonist peptide for research. Acts at the central nervous system level by modulating the neurological pathways of the sexual response. Product intended for research purposes only.

$300,000

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Do you need bacteriostatic water?
To reconstitute this peptide, we recommend that you add Bacteriostatic Water 3 ml ($30.000) to your order.

Frequently Asked Questions

To reconstitute PT-141 10 mg, add 2 ml of bacteriostatic water, obtaining a concentration of 5 mg/ml. Inject subcutaneously. Store refrigerated between 2-8C. Once reconstituted, use within 28 days.

Without reconstitution: store in a cool, dry place away from direct light. Once reconstituted: refrigerate between 2-8C and use within 28 days. Do not freeze the reconstituted solution.

We ship to all Colombia. The estimated delivery time is 1 to 3 business days depending on the city. You receive a tracking number to track your order.

Yes, all our shipments are shipped in discreet packaging, with no logos or indications of the contents on the outside of the package.

All Peptilife products are for scientific research use only. They are not intended for human or animal consumption.

We accept bank transfer, PSE, Nequi and Daviplata. Payment details will be sent upon order confirmation.

Yes, once your order is shipped you will receive a tracking number by mail or WhatsApp to track your order in real time.

Product description

What is PT-141?

PT-141, also known as Bremelanotide, is a synthetic peptide derived from Melanotan II that acts as an agonist of melanocortin receptors, specifically the MC4R receptor. Unlike other compounds that act on the vascular system, PT-141 works directly at the level of the central nervous system, modulating the neurological pathways involved in sexual response and desire.

Mechanism of action of PT-141

The mechanism of action of PT-141 is based on its ability to activate melanocortin type 4 receptors (MC4R) in the hypothalamus. This activation triggers a neuronal signaling cascade that modulates dopaminergic and oxytocinergic pathways associated with arousal and sexual response. By acting directly on the central nervous system, this peptide offers a unique approach that does not rely on peripheral vasodilation.

Research has shown that activation of the MC4R receptor by this compound produces effects on multiple physiological systems, including appetite regulation, energy homeostasis and modulation of sexual behavior. These findings position PT-141 as a peptide of great interest in modern neuropharmacological research.

Researched benefits of PT-141

Preclinical and clinical studies have identified several potential effects associated with PT-141 administration:

  • Modulation of sexual response: PT-141 has demonstrated significant effects on arousal and sexual response in research models, acting through central mechanisms independent of the vascular system.
  • Activation of melanocortin receptors: As a selective agonist of the MC4R, this peptide allows us to study the functions of this receptor in various physiological and behavioral processes.
  • Neuroendocrine regulation: Research suggests that MC4R activation may influence the release of oxytocin and dopamine, key neurotransmitters in modulating social and reproductive behavior.
  • Potential in metabolic research: Given its effect on melanocortin pathways, PT-141 is also being studied in the context of the regulation of energy balance and metabolism.

Research applications

PT-141 has been extensively studied in the context of neuroscience and melanocortin receptor pharmacology. Major areas of research include understanding the central mechanisms of sexual response, studying MC4R signaling pathways and their role in behavioral regulation, as well as exploring novel therapeutic targets for dysfunctions related to the melanocortin system.

Research with PT-141 has also contributed significantly to the understanding of the interaction between the melanocortin, dopaminergic and oxytocinergic systems, opening new perspectives for translational neuroscience research.

Scientific background of PT-141

The development of PT-141 stems from research with Melanotan II, a peptide originally designed to study skin pigmentation. During initial trials, researchers observed that activation of melanocortin receptors produced effects on multiple physiological systems beyond melanogenesis. This observation led to the development of PT-141 as a more selective analogue for the MC4R receptor, with a pharmacokinetic profile optimized for research.

The melanocortin receptors constitute a family of five G protein-coupled receptors (MC1R to MC5R), each with specific functions in different tissues. MC4R, the main target of PT-141, is predominantly expressed in the central nervous system and plays a key role in the regulation of energy balance, autonomic function and reproductive behavior. The ability of PT-141 to selectively activate this receptor makes it a valuable tool for neuroscience research.

Why choose PT-141 from Peptilife Colombia?

At Peptilife Colombia we offer PT-141 of the highest quality, with a purity higher than 98% verified by high performance liquid chromatography (HPLC). Each vial undergoes rigorous quality controls to ensure the consistency and reliability researchers need. We offer secure shipping throughout Colombia with specialized packaging that protects the integrity of the product.

Product specifications

  • Name: PT-141 (Bremelanotide)
  • Presentation: 10 mg per vial
  • Purity: ≥98% verified by HPLC
  • Shape: Lyophilized powder
  • Storage: Store at -20°C. Once reconstituted, store at 2-8°C.

Product intended for research purposes only. Not for human or veterinary use.

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